Institute of Mineral Research

Life Sciences - Health & Wellness

  • Home
  • Open Access
  • Mineral Elements
  • Conditions A-Z
  • Submissions
  • About Us

The association between dietary factors and gestational hypertension and pre-eclampsia: a systematic review and meta-analysis of observational studies

Authors: Schoenaker D, Soedamah-Muthu SS, Mishra GD

Citation: BMC Med 2014 Sep;12(1):157
PMID : 25241701, Journal: BMC Med, 12, 1
Date created: 2014-09-22

Abstract

BackgroundDietary factors have been suggested to play a role in the prevention of hypertensive disorders of pregnancy (HDP), including gestational hypertension and pre-eclampsia, but inconsistent findings have been reported. A systematic review and meta-analyses were performed to synthesize evidence from observational studies of reproductive-aged women on the association between dietary factors and HDP.MethodsMEDLINE and EMBASE were searched to identify studies published until the end of May 2014. Studies were included if they were observational studies of reproductive-age women and reported results on dietary factors (energy, nutrients, foods or overall dietary patterns, alone or in combination with dietary supplements) and gestational hypertension and/or pre-eclampsia. Studies were excluded if they reported on supplements not in combination with dietary intake, or examined a biomarker of dietary intake. Random effects meta-analyses were performed on calculated weighted mean differences (WMD) of dietary intake between cases and non-cases, and effect estimates were pooled.ResultsIn total, 23 cohort and 15 case¿control studies were identified for systematic review, of which 16 could be included in the meta-analyses. Based on meta-analyses of cohort studies, unadjusted energy intake was higher for pre-eclampsia cases (WMD 46 kcal/day, 95% confidence interval (CI) ¿13.80 to 106.23; I 2¿=¿23.9%, P¿=¿0.26), although this was not statistically significant. Unadjusted intakes of magnesium (WMD 8 mg/day, 95% CI ¿13.99 to ¿1.38; I 2¿=¿0.0%, P¿=¿0.41) and calcium (WMD 44 mg/day, 95% CI ¿84.31 to ¿3.62, I 2¿=¿51.1%, P¿=¿0.03) were lower for the HDP cases, compared with pregnant women without HDP. Higher calcium intake consistently showed lower odds for HDP after adjustment for confounding factors (OR¿=¿0.76, 95% CI 0.57 to 1.01, I 2¿=¿0.0%, P¿=¿0.79). A few studies examining foods and dietary patterns suggested a beneficial effect of a diet rich in fruit and vegetables on pre-eclampsia, although not all the results were statistically significant.ConclusionsBased on a limited number of studies, higher total energy and lower magnesium and calcium intake measured during pregnancy were identified as related to HDP. Further prospective studies are required to provide an evidence base for development of preventive health strategies, particularly focusing on dietary factors during pre-pregnancy and early pregnancy.

Related Articles

  • The association between carotid intima media thickness and individual dietary components and patterns
  • Association between dietary calcium and phosphorus intakes, dietary calcium/phosphorus ratio and bone mass in the Korean population
  • The Association Between Dietary Selenium Intake and Diabetes: a Cross-sectional Study Among Middle-aged and Older Adults

Filed Under: Journal Publications Tagged With: eclampsia, gestational hypertension, Magnesium

SEARCH

Silicon Biochemistry

Silicon as an Essential Trace Element in Animal Nutrition
Author: Edith Muriel Carlisle
READ FULL ARTICLE HERE (PDF)

Published in 1899

The Physiological Role of Mineral Nutrients

Author: Loew, Oscar, b. 1844 Volume: no.18 Subject: Plant physiology; Plants Assimilation; Minerals Publisher: Washington : G.P.O. Year: 1899 Possible … Read this book online

Most Recent Posts

  • Update on Nutrients Involved in Maintaining Healthy Bone
  • Lithium as a Nutrient
  • Does Potassium Deficiency Contribute to Hypertension in Children and Adolescents?
  • Iodine deficiency: Clinical implications.

View by Category

  • Clinical Trials / Studies
  • Elements
  • Journal Publications
  • Open Access
  • Seawater
  • Elements
  • Open Access
  • Journal Publications
  • Clinical Trials / Studies
About Us
About Open Access
For Authors
Our Contributors and Partners
Contact
Privacy
Terms & Conditions

Copyright ©2014 - 2018 Institute of Mineral Research