The following references have become outdated or may have been superseded by newer science-based publications. Nonetheless, they remain relevant and considered critical information resources. Click on the name of the author to read the publication.
“Iodine: The Universal Nutrient,” Guy E. Abraham, M.D. In textbooks of medicine, endocrinology and thyroidology, the essential element iodine is mentioned only in connection with the most severe forms of deficiency of this nutrient: cretinism, iodine-deficiency induced goiter and hypothyroidism. Many physicians would be surprised to learn that more than a hundred years ago, iodine was called “The Universal Medicine,” and was used in several clinical conditions.
Kopp W. Nutrition, evolution and thyroid hormone levels – a link to iodine deficiency disorders? Med Hypotheses. 2004;62(6):871-5.
Aydin K, Kendirci M, Kurtoglu S, Karakucuk EI, Kiris A. Iodine and selenium deficiency in school-children in an endemic goiter area in Turkey. J Pediatr Endocrinol Metab. 2002 Jul-Aug;15(7):1027-31
Markou KB, Georgopoulos NA, Makri M, Anastasiou E, Vlasopoulou B, Lazarou N, Deville L, Megreli C, Vagenakis GA, Sakellaropoulos GC, Jabbarov R, Kerimova MG, Mamedgasanov RM, Vagenakis AG. Iodine deficiency in Azerbaijan after the discontinuation of an iodine prophylaxis program: reassessment of iodine intake and goiter prevalence in school children. Thyroid. 2001 Dec;11(12):1141-6.
Squatrito S, Vigneri R, Runello F, Ermans AM, Polley RD, Ingbar SH. Prevention and treatment of endemic iodine-deficiency goiter by iodination of a municipal water supply. J Clin Endocrinol Metab. 1986 Aug;63(2):368-75.
Protection from Radiation
Frankfort SV, Roos JC, Franssen EJ. [Iodine prophylaxis to prevent radiation damage following nuclear disasters] Ned Tijdschr Geneeskd. 2003 Aug 23;147(34):1641-4.
Takamura N, Nakamura Y, Ishigaki K, Ishigaki J, Mine M, Aoyagi K, Yamashita S. Thyroid Blockade during a Radiation Emergency in Iodine-rich Areas: Effect of a Stable-iodine Dosage. J Radiat Res (Tokyo). 2004 Jun;45(2):201-4.
Shakhtarin VV, Tsyb AF, Stepanenko VF, Orlov MY, Kopecky KJ, Davis S. Iodine deficiency, radiation dose, and the risk of thyroid cancer among children and adolescents in the Bryansk region of Russia following the Chernobyl power station accident. Int J Epidemiol. 2003 Aug;32(4):584-91.
Abraham, G.E, MD, and J.D. Flechas, MD, The Effect of Daily Ingestion of 100 mg Iodine Combined with High Doses of Vitamins B2 and B3 (ATP Cofactors) in Five Subjects with Fibromyalgia. The Original Internist, Vol. 15, No. 1, pg. 8-15, March 2008
Abraham, G.E, MD, Facts about Iodine and Autoimmune Thyroiditis. The Original Internist, Vol. 15, No. 2, pg. 75-76, June 2008
Abraham, G.E, MD, The bioavailability of iodine applied to the skin. The Original Internist, Vol. 15, No. 2, pg. 77-79, June 2008
Abraham, G.E, MD, and David Brownstein, MD, A Simple Procedure Combining The Evaluation of Whole Body Sufficiency for Iodine with The Efficiency of the Body To Utilize Peripherall Iodide: The Triple Test. The Original Internist, Vol. 14, No. 1, 17-23, March 2007
Abraham, G.E, MD, and J.D. Flechas, MD, Evidence of Defective Cellular Oxidation and Organification of Iodide in a Female with Fibromyalgia and Chronic Fatigue. The Original Internist, Vol. 14, 77-82, 2007
Abraham, G.E., The History of Iodine in Medicine Part II: The Search for and the Discovery of Thyroid Hormones. The Original Internist, 13: 67-70, June 2006
Abraham, G.E., The History of Iodine in Medicine Part III: Thyroid Fixation and Medical Iodophobia.The Original Internist, 13: 71-78, June 2006
Abraham, G.E, MD, Roxanne C. Handal, BS & John C. Hakala, RPhA. Simplified Procedure for the Measurement of Urine Iodide Levels by the Ion-Selective Eleectrode Assay in a Clinical Setting. The Original Internist, Vol 13, No. 3, 125-135, September 2006
Abraham, G.E.,The Combined Measurement of the Four Stable Halides by the Ion-Selective Electrode Procedure Following Their Chromatographic Separation on a Strong Anion Exchanger Resin: Clinical Applications. The Original Internist, 171-195, December 2006
Abraham, G.E., Serum inorganic iodide levels following ingestion of a tablet form of Lugol solution: Evidence for an enterohepatic circulation of iodine. The Original Internist, 11(3):112-118, 2005
Abraham, G.E., The historical background of the iodine project. The Original Internist, 12(2):57-66, 2005
Brownstein, D., Clinical experience with inorganic, non-radioactive iodine/iodide. The Original Internist, 12(3):105-108, 2005
Flechas, J.D., Orthoiodosupplementation in a primary care practice. The Original Internist, 12(2):89-96, 2005.
Abraham, G.E., Brownstein, D., Evidence that the administration of Vitamin C improves a defective cellular transport mechanism for iodine: A case report. The Original Internist, 12(3):125-130, 2005
Abraham, G.E., Brownstein, D., Validation of the orthoiodosupplementation program: A Rebuttal of Dr. Gaby’s Editorial on iodine. The Original Internist, 12(4): 184-194, 2005
Abraham, G.E., Brownstein, D., Flechas, J.D., The saliva/serum iodide ratio as an index of sodium/iodide symporter efficiency. The Original Internist, 12(4): 152-156, 2005.
Abraham, G.E.,The Wolff-Chaikoff Effect: Crying Wolf? The Original Internist, 12(3):112-118,2005
Abraham, G.E., Flechas, J.D., Hakala, J.C., Measurement Of Urinary Iodide Levels By Ion-Selective Electrode: Improved Sensitivity And Specificity By Chromatography On An Ion-Exchange Resin. The Original Internist, 11(4):19-32,2004
Abraham, G.E., The safe and effective implementation of orthoiodosupplementation in medical practice. The Original Internist, 11:17-36, 2004
Abraham, G.E., The concept of orthoiodosupplementation and its clinical implications. The Original Internist, 11(2):29-38, 2004
Abraham, G.E., Flechas, J.D., Hakala, J.C., Optimum Levels of Iodine for Greatest Mental and Physical Health. The Original Internist, 9:5-20, 2002
Abraham, G.E., Flechas, J.D., Hakala, J.C., Orthoiodosupplementation: Iodine Sufficiency Of The Whole Human Body. The Original Internist, 9:30-41, 2002