Institute of Mineral Research

Life Sciences - Health & Wellness

  • Home
  • Open Access
  • Mineral Elements
  • Conditions A-Z
  • Submissions
  • About Us

Does magnesium supplementation improve body composition and muscle strength in middle-aged overweight women? A double-blind, placebo-controlled, randomized clinical trial

Authors: Moslehi N, Vafa M, Sarrafzadeh J, Rahimi-Foroushani A

Citation: Biol Trace Elem Res 2013 Jun;153(1-3):111-8

PMID : 23619906, Journal: Biol Trace Elem Res, 153, 1-3

Date created: 2013-05-30

Abstract

Muscle strength, an independent predictor of metabolic disorders, disability, and mortality, reduces gradually with advancing age. Little is known about the influence of nutritional intervention on muscle strength in middle-aged. The aim of the present study is to examine whether magnesium could improve body composition and muscle strength in middle-aged overweight women. In this double-blinded, placebo-controlled, randomized trial, a total of 74 healthy middle-aged overweight women (25 ≤ BMI ≤ 30 kg/m(2)) received either 250 mg magnesium in the form of magnesium oxide or placebo daily for 8 weeks. Body composition was assessed using Bioelectrical Impedance Analysis (BIA). Handgrip strength and knee extension strength were measured with isometric dynamometry. Functional mobility was assessed using Time Get Up and Go Test (TGUG). A significant increase in mean lean body mass was observed (P = 0.05) accompanied with a significant decrease in fat mass (P = 0.02) solely in the magnesium group at the end of 8 weeks compared to baseline values but the changes did not reach significant as compared to placebo group. Handgrip strength and TGUG improved in the magnesium group compared to baseline but they were not significant compared to placebo. There were no significant differences in increasing knee extension strength in the magnesium group as compared with placebo. Baseline values of serum magnesium and muscle strength of participants did not indicate any influences on response to magnesium supplementation. Our findings indicate that magnesium as magnesium oxide, 250 mg/day, for 8 weeks do not lead to a significant greater gain in muscle strength and function compared to placebo.

Related Articles

  • Oral magnesium supplementation decreases C-reactive protein levels in subjects with prediabetes and hypomagnesemia: a clinical randomized double-blind placebo-controlled trial
  • The BRAzil MAGnesium (BRAMAG) trial: a randomized clinical trial of oral magnesium supplementation in pregnancy for the prevention of preterm birth and perinatal and maternal morbidity
  • Zinc supplementation for neonatal hyperbilirubinemia: a randomized controlled trial

Filed Under: Clinical Trials / Studies Tagged With: Magnesium. muscle tone

SEARCH

Silicon Biochemistry

Silicon as an Essential Trace Element in Animal Nutrition
Author: Edith Muriel Carlisle
READ FULL ARTICLE HERE (PDF)

Published in 1899

The Physiological Role of Mineral Nutrients

Author: Loew, Oscar, b. 1844 Volume: no.18 Subject: Plant physiology; Plants Assimilation; Minerals Publisher: Washington : G.P.O. Year: 1899 Possible … Read this book online

Most Recent Posts

  • Update on Nutrients Involved in Maintaining Healthy Bone
  • Lithium as a Nutrient
  • Does Potassium Deficiency Contribute to Hypertension in Children and Adolescents?
  • Iodine deficiency: Clinical implications.

View by Category

  • Clinical Trials / Studies
  • Elements
  • Journal Publications
  • Open Access
  • Seawater
  • Elements
  • Open Access
  • Journal Publications
  • Clinical Trials / Studies
About Us
About Open Access
For Authors
Our Contributors and Partners
Contact
Privacy
Terms & Conditions

Copyright ©2014 - 2018 Institute of Mineral Research